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Thorlabs fiber optic patch cable
Behavior and virus expression during food self-administration training, extinction training, and reinstatement testing. A , Timeline for experiment. Behavioral and fiber photometry data are reported for adult Long–Evans rats (6 male, 5 female). B , Representative image of virus coexpression: left, AAV9-syn-jGCaMP8s-WPRE; middle, AAV2/9-hsyn-rDA3m; and right, overlap of viral expression. The cannula track appears as an oblong shape terminating to the right of the anterior commissure. C <t>,</t> <t>Fiber-optic</t> cannula placement for rats. The dot signifies the end of the cannula (females, pink; males, blue). Placement was determined after immunohistochemistry for GFP and mApple to confirm virus expression at the end of the cannula. Sections adapted from Paxinos & Watson 7th edition. D , Food self-administration sessions (SA1–4), extinction sessions (Ext1–6), and reinstatement tests. Left, Active lever presses for all rats ( n = 11) across all sessions for all behavioral phases. Right, Inactive lever presses for the same sessions. E , Data from D graphed to show direct comparison of SA4, Ext6, Cue-primed reinstatement, and Pellet + Cue-primed reinstatement (*** p < 0.0001, * p < 0.05). Error bars indicate mean (±SEM) for each session while dots represent individual rats. AP, anterior posterior; ac, anterior commissure; NAcc, nucleus accumbens core. Full statistical output for experiments shown in this figure is presented in . Additional analyses related to data in this figure are presented in Extended Data .
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Behavior and virus expression during food self-administration training, extinction training, and reinstatement testing. A , Timeline for experiment. Behavioral and fiber photometry data are reported for adult Long–Evans rats (6 male, 5 female). B , Representative image of virus coexpression: left, AAV9-syn-jGCaMP8s-WPRE; middle, AAV2/9-hsyn-rDA3m; and right, overlap of viral expression. The cannula track appears as an oblong shape terminating to the right of the anterior commissure. C , Fiber-optic cannula placement for rats. The dot signifies the end of the cannula (females, pink; males, blue). Placement was determined after immunohistochemistry for GFP and mApple to confirm virus expression at the end of the cannula. Sections adapted from Paxinos & Watson 7th edition. D , Food self-administration sessions (SA1–4), extinction sessions (Ext1–6), and reinstatement tests. Left, Active lever presses for all rats ( n = 11) across all sessions for all behavioral phases. Right, Inactive lever presses for the same sessions. E , Data from D graphed to show direct comparison of SA4, Ext6, Cue-primed reinstatement, and Pellet + Cue-primed reinstatement (*** p < 0.0001, * p < 0.05). Error bars indicate mean (±SEM) for each session while dots represent individual rats. AP, anterior posterior; ac, anterior commissure; NAcc, nucleus accumbens core. Full statistical output for experiments shown in this figure is presented in . Additional analyses related to data in this figure are presented in Extended Data .

Journal: eNeuro

Article Title: Dopamine and Calcium Dynamics in the Nucleus Accumbens Core during Food Seeking

doi: 10.1523/ENEURO.0380-25.2026

Figure Lengend Snippet: Behavior and virus expression during food self-administration training, extinction training, and reinstatement testing. A , Timeline for experiment. Behavioral and fiber photometry data are reported for adult Long–Evans rats (6 male, 5 female). B , Representative image of virus coexpression: left, AAV9-syn-jGCaMP8s-WPRE; middle, AAV2/9-hsyn-rDA3m; and right, overlap of viral expression. The cannula track appears as an oblong shape terminating to the right of the anterior commissure. C , Fiber-optic cannula placement for rats. The dot signifies the end of the cannula (females, pink; males, blue). Placement was determined after immunohistochemistry for GFP and mApple to confirm virus expression at the end of the cannula. Sections adapted from Paxinos & Watson 7th edition. D , Food self-administration sessions (SA1–4), extinction sessions (Ext1–6), and reinstatement tests. Left, Active lever presses for all rats ( n = 11) across all sessions for all behavioral phases. Right, Inactive lever presses for the same sessions. E , Data from D graphed to show direct comparison of SA4, Ext6, Cue-primed reinstatement, and Pellet + Cue-primed reinstatement (*** p < 0.0001, * p < 0.05). Error bars indicate mean (±SEM) for each session while dots represent individual rats. AP, anterior posterior; ac, anterior commissure; NAcc, nucleus accumbens core. Full statistical output for experiments shown in this figure is presented in . Additional analyses related to data in this figure are presented in Extended Data .

Article Snippet: They were connected to a fiber-optic patch cable (Thorlabs Custom: FP-400URT, 0.5NA, 0.4 m length, FT023SS tubing with a 2.5 mm stainless steel ferrule) via a ceramic connector (Thorlabs, ADAF1-5), and the cable was passed through the top of the box and attached to a steel arm with a counterweight (Med Associates, PHM-110-SAI).

Techniques: Virus, Expressing, Immunohistochemistry, Comparison